EL-ANA ProfilesTM: anti-chromatin is used for the detection and measurement of IgG autoantibodies directed against chromatin or nucleosomes (H1 strpped). The combination of Histone and DNA form uniques antigenic determinants. It is found mainly in SLE, both idiopathic and drug-induced. The wells are coated with purified native H1 stripped chromatin for highest sensitivity and >95% specificity.
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Last Updated : 03/16/2013