When we breathe spontaneously under normal conditions the upper airway is designed to effectively filter, heat and humidify the air. Depending on ambient conditions, inhaled gas is heated to 37°C and humidified to 100% relative humidity. The point where the gas is fully heated and humidified is called the isothermic saturation boundary and typically occurs before the fourth or fifth generation of subsegmental bronchi.
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Last Updated : 03/16/2013