Home > Specialties > IVD Test Reagent/Kits, Molecular Assay, Gene Anomaly, Deletion/Duplication, HER2/NEU

IVD Test Reagent/Kits, Molecular Assay, Gene Anomaly, Deletion/Duplication, HER2/NEU

Definition : Molecular assay reagents intended to identify deletions or duplications of the HER2/NEU gene, located at chromosome 17q12, which encodes the protein receptor tyrosine-protein kinase erbB-2. Genetic variants at this locus have been associated with susceptibility to glioma and response to the drugs pertuzumab and trastuzumab. Somatic mutations in HER2 have been observed in breast, gastric, and lung cancers.

Entry Terms : "Breast Cancer Gene Anomaly Detection Reagents" , "CD340 Deletion/Duplication Detection Reagent Kits" , "Erb-B2 Receptor Tyrosine Kinase 2 Deletion/Duplication Detection Reagents" , "ERBB2 Deletion/Duplication Detection Reagent Kits" , "Gastric Cancer Gene Anomaly Detection Reagents" , "Glioma Susceptibility 1 (GLM1) Gene Anomaly Detection Reagents" , "Lung Cancer Gene Anomaly Detection Reagents" , "MLN 19 Deletion/Duplication Detection Reagent Kits" , "NGL Deletion/Duplication Detection Reagent Kits" , "Pertuzumab (Perjeta) Companion Diagnostic Test Reagents" , "TKR1 Deletion/Duplication Detection Reagent Kits" , "Trastuzumab (Herceptin) Companion Diagnostic Test Reagents"

UMDC code : 36668

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