IVD Test Reagent/Kits, Molecular Assay, Gene Anomaly, Mutation, VHL
Definition : Molecular assay reagents intended to identify mutations in the von Hippel-Lindau tumor suppressor (VHL) gene, located at chromosome 3p26-p25, a tumor which makes a protein that is part of a complex (VCB) that targets other proteins to be broken down in the cell. This inherited genetic mutation has been identified in patients with clear cell renal cancer and Von Hippel-Lindau syndrome; it is also associated with hereditary renal cell carcinoma and polycythemia.
Entry Terms : "Polycythemia Chuvash Polycythemia Gene Mutation Reagents" , "Hereditary Renal Cell Carcinoma Gene Mutation Reagents" , "Von Hippel-Lindau (VHL) Syndrome Gene Mutation Reagents" , "VHL Gene Mutation Detection Reagents" , "Reagents, Molecular Assay, Gene Anomaly, Mutation, VHL"
UMDC code : 25008